KIT anticorps
Aperçu rapide pour KIT anticorps (ABIN375629)
Antigène
Voir toutes KIT AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- Chicken c-Kit, Mr 145 kDa
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Attributs du produit
- Mouse Anti-Chicken c-Kit-UNLB
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Purification
- Purified
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Immunogène
- Sp/chkit4A4 cells (Sp2/0 cells transfected with chicken c-Kit cDNA)
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Isotype
- IgG2a
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Indications d'application
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- Applications: FC - Quality tested
- Working Dilutions: Flow Cytometry Purified (UNLB) antibody 1 g/106 cells FITC and BIOT conjugates 1 g/106 cells PE conjugates 0.2 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L
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Volume d'échantillon
- 1 mL
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Restrictions
- For Research Use only
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Concentration
- 0.5 mg/mL
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Buffer
- 0.5 mg of purified immunoglobulin in 1.0 mL of borate buffered saline, pH 8.2. No preservatives or amine-containing buffer salts added
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Agent conservateur
- Without preservative
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Conseil sur la manipulation
- Each reagent is stable for the period shown on the bottle label if stored as directed.
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Stock
- 4 °C
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Stockage commentaire
- Store at 2-8°C
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- KIT (Mast/stem Cell Growth Factor Receptor (KIT))
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Autre désignation
- c-Kit
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Sujet
- C-Kit is a 145 kDa transmembrane receptor-type protein tyrosine kinase encoded by the c-Kit proto-oncogene and is the receptor for stem cell factor (SCF). c-Kit acts to regulate a variety of biological responses including cell proliferation, apoptosis, chemotaxis and adhesion. The amino acid sequence of chicken c-kit shows 63 % identity to mouse c-Kit and exhibits similar expression patterns in RNA blot analysis suggesting similar biological roles.
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Pathways
- Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Sensory Perception of Sound, Stem Cell Maintenance, Production of Molecular Mediator of Immune Response, Regulation of long-term Neuronal Synaptic Plasticity
Antigène
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